Bromo-PEG2-CH2-Boc

• CAT Number: I016465
• CAS Number: 1807518-63-3
• Molecular Formula: C₁₀H₁₉BrO₄
• Molecular Weight: 283.16
• Purity: ≥95%
• Target: PROTAC Linkers

Bromo-PEG2-CH2-Boc (CAT: I016465) is a compound that consists of a bromo group, a polyethylene glycol (PEG) linker, a methylene spacer, and a tert-butoxycarbonyl (Boc) protecting group. It is commonly used as a building block in organic synthesis and drug development. The PEG linker provides water solubility and flexibility, while the Boc group serves as a temporary protecting group that can be removed under specific conditions to reveal reactive functional groups for further chemical reactions. The bromo group can be utilized for various cross-coupling reactions and modifications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562