Bromo-PEG5-Boc

• CAT Number: I016469
• CAS Number: 1415800-38-2
• Molecular Formula: C₁₇H₃₃BrO₇
• Molecular Weight: 429.34
• Purity: ≥95%
• Target: PROTAC Linkers

Bromo-PEG5-Boc (CAT: I016469) is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs (PROteolysis TAgeting Chimeras). This linker contains a bromo functional group that can be used for conjugation with other molecules, allowing for the creation of targeted protein degraders. PROTACs are innovative molecules designed to selectively degrade specific target proteins within cells, offering a promising approach for therapeutic interventions.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562