Bromoacetamido-C2-PEG2-NH-Boc

• CAT Number: I016594
• CAS Number: 182244-33-3
• Molecular Formula: C₁₃H₂₅BrN₂O₅
• Molecular Weight: 369.25
• Purity: ≥95%
• Target: PROTAC Linkers

Bromoacetamido-C2-PEG2-NH-Boc (CAT: I016594) is a compound consisting of a bromoacetamido group, a PEG (polyethylene glycol) spacer with two ethylene glycol units, and a Boc-protected amino group. The bromoacetamido group serves as a reactive handle for further functionalization or conjugation, while the PEG spacer provides flexibility and water solubility. The Boc protecting group on the amino group can be removed under appropriate conditions to expose the amine for subsequent reactions. Bromoacetamido-C2-PEG2-NH-Boc is commonly used in bioconjugation chemistry to link molecules or surfaces through the bromoacetamido group, allowing for controlled and selective modification. Its versatile nature and chemical stability make it valuable in various biomedical and bioengineering applications.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562