Bromoacetamido-PEG3-C2-Boc

• CAT Number: I016452
• CAS Number: 1807537-33-2
• Molecular Formula: C₁₅H₂₈BrNO₆
• Molecular Weight: 398.29
• Purity: ≥95%
• Target: PROTAC Linkers

Bromoacetamido-PEG3-C2-Boc(CAT: I016452) is a notable compound with applications in pharmaceutical and chemical synthesis, particularly in the realm of drug delivery and molecular modification. This compound features a bromoacetamido group, a PEG spacer of three units, and a tert-butyloxycarbonyl (Boc) protecting group on a C2 carbon. Such a structure is crucial for functionalizing molecules, enabling controlled conjugation, modification, or prodrug design. The bromoacetamido group adds reactivity for selective transformations, the PEG spacer imparts water solubility and biocompatibility, and the Boc protection ensures controlled reactivity.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562