Bromodomain inhibitor-8

• CAT Number: I018647
• CAS Number: 1300031-70-2
• Molecular Formula: C26H25ClN2O3
• Molecular Weight: 448.94
• Purity: ≥95%
• Synonyms: methyl 4-[(2S,4R)-1-acetyl-4-(4-chloroanilino)-2-methyl-3,4-dihydro-2H-quinolin-6-yl]benzoate
• InChI: InChI=1S/C26H25ClN2O3/c1-16-14-24(28-22-11-9-21(27)10-12-22)23-15-20(8-13-25(23)29(16)17(2)30)18-4-6-19(7-5-18)26(31)32-3/h4-13,15-16,24,28H,14H2,1-3H3/t16-,24+/m0/s1
• InChIKey: UUWRMPUSYYZXJY-UPCLLVRISA-N
• SMILES: CC1CC(C2=C(N1C(=O)C)C=CC(=C2)C3=CC=C(C=C3)C(=O)OC)NC4=CC=C(C=C4)Cl

Bromodomain inhibitor-8 (Intermediate 21) is a BET bromodomain inhibitor for treating autoimmune and inflammatory diseases[1].

Reference

[1]. CHUNG, Chun-Wa, et al. BROMODOMAIN INHIBITORS FOR TREATING AUTOIMMUNE AND INFLAMMATORY Dl SEASES. WO 2011/054843 Al.