Bromoenol lactone

• CAT Number: I011733
• CAS Number: 88070-98-8
• Molecular Formula: C16H13BrO2
• Molecular Weight: 317.182
• Purity: ≥95%
• Synonyms: 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one
• Target: Phospholipase
• Solubility: Soluble in DMSO
• Storage: Store at -20C
• IUPAC Name: (6E)-6-(bromomethylidene)-3-naphthalen-1-yloxan-2-one
• InChI: InChI=1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
• InChIKey: BYUCSFWXCMTYOI-ZRDIBKRKSA-N
• SMILES: C1CC(=CBr)OC(=O)C1C2=CC=CC3=CC=CC=C32

Bromoenol lactone(CAT: I011733) is a chemical compound used in research as a potent inhibitor of calcium-independent phospholipase A2 (iPLA2), an enzyme involved in the hydrolysis of membrane phospholipids. iPLA2 has been implicated in several diseases, including Alzheimer’s disease, multiple sclerosis, and cancer, making it an attractive target for drug development. Bromoenol lactone is typically administered in vitro or in animal models for research purposes.