Brompheniramine, (R)-

For research use only. Not for therapeutic Use.

  • CAT Number: I023732
  • CAS Number: 32656-44-3
  • Molecular Formula: C16H19BrN2
  • Molecular Weight: 319.246
  • Purity: 98%
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Brompheniramine, (R)- is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.


Catalog Number I023732
CAS Number 32656-44-3
Synonyms

Brompheniramine, (R)-; Dimetapp; (-)-Brompheniramine; (R)-Brompheniramine; L-Brompheniramine

Molecular Formula C16H19BrN2
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (gammaR)-gamma-(4-Bromophenyl)-N,N-dimethyl-2-pyridinepropanamine
InChI InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m1/s1
InChIKey ZDIGNSYAACHWNL-OAHLLOKOSA-N
SMILES CN(C)CC[C@H](C1=CC=C(Br)C=C1)C2=NC=CC=C2
Reference

1. Simons FE, Frith EM, Simons KJ (December 1982). "The pharmacokinetics and antihistaminic effects of brompheniramine". The Journal of Allergy and Clinical Immunology. 70 (6): 458–64. doi:10.1016/0091-6749(82)90009-4. PMID 6128358.
2. Barondes, Samuel H. (2003). Better Than Prozac. New York: Oxford University Press. pp. 39–40. ISBN 0-19-515130-5.
3. Salahudeen MJ; Duffull SB; Nishtala PS; et al. (2015-03-25). "Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review". BMC Geriatrics. 15 (31). doi:10.1186/s12877-015-0029-9. PMC 4377853. PMID 25879993.
4. L.A. Walter, U.S. Patent 3,061,517 (1962)
5. L.A. Walter, U.S. Patent 3,030,371 (1962)

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