Broxyquinoline

For research use only. Not for therapeutic Use.

  • CAT Number: A000812
  • CAS Number: 521-74-4
  • Molecular Formula: C9H5Br2NO
  • Molecular Weight: 302.95
  • Purity: ≥95%
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Broxyquinoline(Cat No.:A000812)is an antiseptic and antimicrobial compound used in the treatment of infections. It acts by inhibiting bacterial growth and has been utilized in various therapeutic applications, particularly for skin and mucosal infections. Its mechanism involves interfering with the cellular processes of pathogens, disrupting their ability to replicate and survive. While it has shown efficacy in laboratory settings, it is primarily used in conjunction with other agents to enhance therapeutic outcomes. Broxyquinoline’s broad-spectrum antimicrobial activity makes it a valuable component in the management of bacterial infections.


Catalog Number A000812
CAS Number 521-74-4
Synonyms

5,7-Dibromoquinolin-8-ol; 521-74-4; 5,7-Dibromo-8-hydroxyquinoline; 5,7-Dibromo-8-quinolinol; Broxiquinoline

Molecular Formula C9H5Br2NO
Purity ≥95%
Target Parasite
Storage -20°C
IUPAC Name 5,7-dibromoquinolin-8-ol
InChI InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChIKey ZDASUJMDVPTNTF-UHFFFAOYSA-N
SMILES C1=CC2=C(C(=C(C=C2Br)Br)O)N=C1
Reference

1: Swain R, Bapna JS. Impairment of exercise tolerance due to
broxyquinoline-brobenzoxaldine combination. Hum Toxicol. 1986 Jan;5(1):63-4.
PubMed PMID: 3081430.
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2: Swain R, Bapna JS, Das AK, Chandrasekar S, Swaminathan RP, Bosco B, Veliath S,
Thombre DP. A study on the neurotoxicity of broxyquinoline and brobenzoxaldine
combination in therapeutic doses. Hum Toxicol. 1986 Jan;5(1):35-41. PubMed PMID:
3081428.
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3: Hazra SK, Ghosh S, Kundu SK, Chaudhuri S. Therapeutic trial of a combination
of broxyquinoline and brobenzoxaldine in the treatment of leprosy. Lepr India.
1979 Oct;51(4):505-10. PubMed PMID: 118304.

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4: Edibam BM. Comparative study of the efficacy of chloramphenicol and a
combination of chloramphenicol, broxyquinoline and brobanzoxaldine in the
treatment of enteric fever. Indian Pediatr. 1975 Jul;12(7):587-91. PubMed PMID:
810421.

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5: Sharma CS. Letter: Effect of broxyquinoline and broxaldine in leprosy. Lancet.
1975 Feb 15;1(7903):405. PubMed PMID: 46561.
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6: Rao SR, Rajyalaxmi K, Murthy KJ, Chandrasekhar VP. Anti-fungal activity of
broxyquinoline and brobenzoxaldine. J Assoc Physicians India. 1973
Mar;21(3):295-8. PubMed PMID: 4792779.

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7: Shah AP, Phatak AT. A clinical trial of broxyquinoline–brobenzoxalidine in
childhood diarrhoea. Indian J Pediatr. 1973 Mar;40(302):83-92. PubMed PMID:
4585812.

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8: Bengtsson K, Vikrot O. [Retrograde amnesia after broxyquinoline intake].
Lakartidningen. 1972 Jun 12;69:Suppl 2:14-6. Swedish. PubMed PMID: 4645695.
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9: Majumdar M, Majumdar H. Broxyquinoline and brobenzoxaldine with belladonna in
childhood diarrhoeas. Indian Pediatr. 1971 Feb;8(2):65-7. PubMed PMID: 5560455.

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10: Manchanda SS, Grover L, Bhushan S, Lal H. Broxyquinoline and brobenzoxalidine
suspension (Intestopan-AI 307) in childhood diarrhoea. A clinical trial on 533
children. Indian J Pediatr. 1970 May;37(268):177-84. PubMed PMID: 4933138.

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