Bruceantin

• CAT Number: I003504
• CAS Number: 41451-75-6
• Molecular Formula: C28H36O11
• Molecular Weight: 548.58
• Purity: ≥95%
• Target: Disease Research Fields
• Solubility: DMSO 10 mg/ml
• Storage: Store at -20C

Bruceantin(CAT: I003504) is a natural product derived from the plant Brucea javanica. It is a complex mixture of quassinoids, which are known for their cytotoxic and antitumor properties. Bruceantin has shown potential as an anticancer agent by inhibiting protein synthesis and inducing apoptosis in cancer cells. It has been investigated for its activity against various types of cancer, including leukemia, breast cancer, and lung cancer. Clinical studies are ongoing to evaluate its efficacy and safety as a potential treatment option for cancer patients.

Reference

[1]. Cuendet M, et al. Antitumor activity of bruceantin: an old drug with new promise. J Nat Prod. 2004 Feb;67(2):269-72.
[2]. Cuendet M, et al. Multiple myeloma regression mediated by bruceantin. Clin Cancer Res. 2004 Feb 1;10(3):1170-9.