BSH-IN-1

• CAT Number: I023748
• CAS Number: 2553217-91-5
• Molecular Formula: C25H41FO3
• Molecular Weight: 408.59
• Purity: 98%
• Synonyms: BSH-IN-1; BSH IN-1; BSH-IN 1; BSH IN 1
• Target: Bacterial
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Store at -20°C
• IUPAC Name: (5R)-5-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-1-fluorohexan-2-one
• InChI: InChI=1S/C25H41FO3/c1-15(4-5-18(28)14-26)19-6-7-20-23-21(9-11-25(19,20)3)24(2)10-8-17(27)12-16(24)13-22(23)29/h15-17,19-23,27,29H,4-14H2,1-3H3/t15-,16+,17-,19-,20+,21+,22-,23+,24+,25-/m1/s1
• InChIKey: XDVGNIBMZHDZLL-GDQMVUAZSA-N
• SMILES: C[C@H](CCC(=O)CF)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C

BSH-IN-1（Cat No.:I023748）is a selective inhibitor targeting bile salt hydrolase (BSH), an enzyme produced by certain gut bacteria that deconjugates bile acids. By inhibiting BSH, BSH-IN-1 preserves conjugated bile acids, which can influence host lipid metabolism, energy balance, and gut health. Research on BSH-IN-1 focuses on its potential to modulate the gut microbiota composition and support metabolic health, offering a novel approach to managing conditions like obesity and metabolic syndrome. This compound is valuable in understanding the complex interactions between gut bacteria, bile acids, and host health outcomes.