Btk inhibitor 1

• CAT Number: I001573
• CAS Number: 1412418-47-3
• Molecular Formula: C22H22N6O
• Molecular Weight: 386.45
• Purity: ≥95%
• Synonyms: 3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• Target: Btk
• Solubility: 10 mM in DMSO
• Storage: Store at -20℃
• InChI: 1S/C22H22N6O/c23-21-19-20(15-8-10-18(11-9-15)29-17-6-2-1-3-7-17)27-28(22(19)26-14-25-21)16-5-4-12-24-13-16/h1-3,6-11,14,16,24H,4-5,12-13H2,(H2,23,25,26)
• InChIKey: GPSQYTDPBDNDGI-UHFFFAOYSA-N
• SMILES: C1CC(CNC1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N

Btk Inhibitor 1 is a selective small molecule inhibitor targeting Bruton’s tyrosine kinase (Btk), an enzyme crucial for B-cell receptor signaling and immune cell function. By inhibiting Btk, this compound shows promise in treating various B-cell malignancies and autoimmune disorders. Its mechanism involves blocking Btk’s activity, which disrupts signaling pathways that promote cell proliferation and survival. Ongoing research aims to further elucidate its efficacy and safety profile in clinical applications, positioning Btk Inhibitor 1 as a potential therapeutic agent in hematological cancers.