BU 224 hydrochloride

• CAT Number: I010287
• CAS Number: 205437-64-5
• Molecular Formula: C12H12ClN3
• Molecular Weight: 233.69
• Purity: ≥95%
• Synonyms: 2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride
• Target: Apoptosis
• Solubility: Soluble to 10 mM in DMSO
• Storage: Store at RT
• IUPAC Name: 2-(4,5-dihydro-1H-imidazol-2-yl)quinoline;hydrochloride
• InChI: InChI=1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H
• InChIKey: DDFHQXAQWZWRSQ-UHFFFAOYSA-N
• SMILES: C1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl

BU 224 hydrochloride (Cat.No:I010287) is a high affinity ligand for the imidazoline I2 binding site (Ki = 2.1 nM). Putative I2 antagonist; antagonizes the effects of imidazoline ligands on morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.