For research use only. Not for therapeutic Use.
BU 224 hydrochloride (Cat.No:I010287) is a high affinity ligand for the imidazoline I<sub>2</sub> binding site (K<sub>i</sub> = 2.1 nM). Putative I<sub>2</sub> antagonist; antagonizes the effects of imidazoline ligands on morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.
| Catalog Number | I010287 |
| CAS Number | 205437-64-5 |
| Synonyms | 2-(4,5-Dihydroimidazol-2-yl)quinoline hydrochloride |
| Molecular Formula | C12H12ClN3 |
| Purity | ≥95% |
| Target | Imidazoline Receptors |
| Solubility | Soluble to 10 mM in DMSO |
| Storage | Store at RT |
| IUPAC Name | 2-(4,5-dihydro-1H-imidazol-2-yl)quinoline;hydrochloride |
| InChI | InChI=1S/C12H11N3.ClH/c1-2-4-10-9(3-1)5-6-11(15-10)12-13-7-8-14-12;/h1-6H,7-8H2,(H,13,14);1H |
| InChIKey | DDFHQXAQWZWRSQ-UHFFFAOYSA-N |
| SMILES | C1CN=C(N1)C2=NC3=CC=CC=C3C=C2.Cl |
