Bumetanide-d5

• CAT Number: S000311
• CAS Number: 1216739-35-3
• Molecular Formula: C17H15D5N2O5S
• Molecular Weight: 369.45
• Purity: ≥95%
• IUPAC Name: 3-(butylamino)-4-(2,3,4,5,6-pentadeuteriophenoxy)-5-sulfamoylbenzoic acid
• InChI: InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)/i4D,5D,6D,7D,8D
• InChIKey: MAEIEVLCKWDQJH-UPKDRLQUSA-N
• SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Bumetanide-d5（Cat No.:S000311） is a deuterated form of bumetanide. Five hydrogen atoms are replaced with deuterium, enhancing its molecular stability and making it useful as an internal standard in analytical methodologies such as mass spectrometry and NMR spectroscopy. Bumetanide is a potent loop diuretic used primarily to treat heart failure, liver cirrhosis, and renal disease by promoting the excretion of water and salts from the body. Incorporating deuterium in bumetanide-d5 aids in the precise investigation of its pharmacokinetics, allowing for a better understanding of its absorption, distribution, metabolism, and excretion.