For research use only. Not for therapeutic Use.
Bunazosin is a potent and selective α1-adrenoceptor antagonist. Bunazosin can be used for antihypertensive and ocular hypotensive research[1].
Catalog Number | I043944 |
CAS Number | 80755-51-7 |
Synonyms | 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,4-diazepan-1-yl]butan-1-one |
Molecular Formula | C19H27N5O3 |
Purity | ≥95% |
InChI | InChI=1S/C19H27N5O3/c1-4-6-17(25)23-7-5-8-24(10-9-23)19-21-14-12-16(27-3)15(26-2)11-13(14)18(20)22-19/h11-12H,4-10H2,1-3H3,(H2,20,21,22) |
InChIKey | RHLJLALHBZGAFM-UHFFFAOYSA-N |
SMILES | CCCC(=O)N1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC |
Reference | [1]. Hideaki Hara , et al. Bunazosin, a selective alpha1-adrenoceptor antagonist, as an anti-glaucoma drug: effects on ocular circulation and retinal neuronal damage. Cardiovasc Drug Rev. Spring 2005;23(1):43-56. |