For research use only. Not for therapeutic Use.
Bupivacaine HCl binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.<br>Bupivacaine solution is cytotoxic to bovine articular chondrocytes and articular cartilage in vitro after only 15 to 30 minutes exposure.<br>Bupivacaine does not only induce Ca2+ release from the sarcoplasmic reticulum (SR) in rats, but also inhibits Ca2+ uptake by the SR, which is mainly regulated by SR Ca2+ adenosine triphosphatase activity.
| Catalog Number | A001211 |
| CAS Number | 18010-40-7 |
| Synonyms | NA |
| Molecular Formula | C18H28N2O.HCl |
| Purity | ≥95% |
| Target | Membrane Transporter/Ion Channel |
| Solubility | >10.3mg/mL in DMSO |
| Storage | 3 years -20C powder |
