For research use only. Not for therapeutic Use.
Busulfan-d8 is a deuterated form of busulfan, an alkylating agent used in chemotherapy for treating chronic myelogenous leukemia and in bone marrow conditioning before transplantation. The eight deuterium atoms in Busulfan-d8 make it an excellent compound for detailed pharmacokinetic and metabolic studies. This isotopic labeling allows researchers to precisely track the drug’s absorption, distribution, metabolism, and excretion using advanced techniques such as NMR spectroscopy and mass spectrometry. Busulfan-d8 aids in understanding the drug’s bioavailability, optimizing therapeutic regimens, and minimizing side effects, contributing significantly to cancer research and treatment optimization.
Catalog Number | R006682 |
CAS Number | 116653-28-2 |
Synonyms | 1,4-Butanediol-d8-dimethanesulfonate Esters; Busulphan-d8; CB-2041-d8; GT-41-d8; Busulfex-d8; Misulban-d8; Myleran-d8; |
Molecular Formula | C6H14O6S2 |
Purity | ≥95% |
Target | Apoptosis |
Storage | -20°C |
IUPAC Name | (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate |
InChI | InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3/i3D2,4D2,5D2,6D2 |
InChIKey | COVZYZSDYWQREU-SQUIKQQTSA-N |
SMILES | [2H]C([2H])(C([2H])([2H])C([2H])([2H])OS(=O)(=O)C)C([2H])([2H])OS(=O)(=O)C |