Busulfan-d8

For research use only. Not for therapeutic Use.

  • CAT Number: R006682
  • CAS Number: 116653-28-2
  • Molecular Formula: C6H14O6S2
  • Molecular Weight: 254.341
  • Purity: ≥95%
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Busulfan-d8 is a deuterated form of busulfan, an alkylating agent used in chemotherapy for treating chronic myelogenous leukemia and in bone marrow conditioning before transplantation. The eight deuterium atoms in Busulfan-d8 make it an excellent compound for detailed pharmacokinetic and metabolic studies. This isotopic labeling allows researchers to precisely track the drug’s absorption, distribution, metabolism, and excretion using advanced techniques such as NMR spectroscopy and mass spectrometry. Busulfan-d8 aids in understanding the drug’s bioavailability, optimizing therapeutic regimens, and minimizing side effects, contributing significantly to cancer research and treatment optimization.


Catalog Number R006682
CAS Number 116653-28-2
Synonyms

1,4-Butanediol-d8-dimethanesulfonate Esters; Busulphan-d8; CB-2041-d8; GT-41-d8; Busulfex-d8; Misulban-d8; Myleran-d8;

Molecular Formula C6H14O6S2
Purity ≥95%
Target Apoptosis
Storage -20°C
IUPAC Name (1,1,2,2,3,3,4,4-octadeuterio-4-methylsulfonyloxybutyl) methanesulfonate
InChI InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3/i3D2,4D2,5D2,6D2
InChIKey COVZYZSDYWQREU-SQUIKQQTSA-N
SMILES [2H]C([2H])(C([2H])([2H])C([2H])([2H])OS(=O)(=O)C)C([2H])([2H])OS(=O)(=O)C

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