Butein

• CAT Number: I003720
• CAS Number: 487-52-5
• Molecular Formula: C15H12O5
• Molecular Weight: 272.25
• Purity: ≥95%
• Synonyms: (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one
• Target: Protein Tyrosine Kinase/RTK
• Solubility: DMSO: ≥ 35 mg/mL
• Storage: 2-8°C
• InChI: InChI=1S/C15H12O5/c16-10-3-4-11(14(19)8-10)12(17)5-1-9-2-6-13(18)15(20)7-9/h1-8,16,18-20H/b5-1+
• InChIKey: AYMYWHCQALZEGT-ORCRQEGFSA-N
• SMILES: C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O

Butein（Cat No.:I003720） is a plant polyphenol extracted from Rhus verniciflua, also known as the Japanese lacquer tree. It exhibits inhibitory effects on the activation of protein tyrosine kinase and the epidermal growth factor receptor (EGFR). By targeting these signaling pathways, butein has the potential to modulate cellular processes involved in cell growth, proliferation, and survival. Its ability to inhibit protein tyrosine kinase and EGFR activation makes it a promising compound for further investigation in the development of therapeutic strategies against diseases associated with dysregulated kinase signaling, such as cancer and inflammatory disorders.