For research use only. Not for therapeutic Use.
Buthiazide is a thiazide diuretic used to treat hypertension and edema associated with congestive heart failure, liver cirrhosis, and renal disorders. It works by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, promoting the excretion of sodium and water, thereby reducing blood pressure and fluid retention. Research on buthiazide focuses on its efficacy, safety profile, and potential side effects, as well as its role in combination therapies for better clinical outcomes.
| Catalog Number | R048092 |
| CAS Number | 2043-38-1 |
| Synonyms | 6-Chloro-3,4-dihydro-3-(2-methylpropyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; Butizid; Butizide; Eunephran; Isobutylhydrochlorothiazide; Modenol; Thiabutazide; |
| Molecular Formula | C11H16ClN3O4S2 |
| Purity | ≥95% |
| Storage | Store at -20°C |
| IUPAC Name | 6-chloro-3-(2-methylpropyl)-1,1-dioxo-3,4-dihydro-2H-1$l^{6} |
| InChI | InChI=1S/C11H16ClN3O4S2/c1-6(2)3-11-14-8-4-7(12)9(20(13,16)17)5-10(8)21(18,19)15-11/h4-6,11,14-15H,3H2,1-2H3,(H2,13,16,17) |
| InChIKey | HGBFRHCDYZJRAO-UHFFFAOYSA-N |
| SMILES | CC(C)CC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl |
