Butyl Methanesulfonate

• CAT Number: R036447
• CAS Number: 1912-32-9
• Molecular Formula: C5H12O3S
• Molecular Weight: 152.208
• Purity: ≥95%
• Synonyms: Butyl Mesylate; Methanesulfonic Acid n-Butyl Ester; NSC 36060; n-Butyl Methanesulfonate
• Storage: RT
• IUPAC Name: butyl methanesulfonate
• InChI: InChI=1S/C5H12O3S/c1-3-4-5-8-9(2,6)7/h3-5H2,1-2H3
• InChIKey: LFLBHTZRLVHUQC-UHFFFAOYSA-N
• SMILES: CCCCOS(=O)(=O)C

Butyl Methanesulfonate (CAS 1912-32-9) is colourless to pale yellow oil, which is a reactant used in the preparation of task-specific ionic liquids. 

Reference

1. Indian J Pharm Sci. 2011 Jan;73(1):107-10. doi: 10.4103/0250-474X.89769.Determination of Alkyl Methanesulfonates in Doxazosin Mesylate by Gas Chromatography-mass Spectrometer.Sitaram C(1), Rupakula RB, Reddy BN, Sastry CS.

 

High sensitive rapid gas chromatography-mass spectrometry method for the determination of four carcinogenic alkyl methanesulfonates viz. methyl methanesulfonate, ethyl methanesulfonate, isopropyl methanesulfonate and n-butyl methanesulfonate in doxazosin mesylate has been presented by using selective ion monitoring mode. The optimum separation was achieved between methyl methanesulfonate, ethyl methanesulfonate, isopropyl methanesulfonate and n-butyl methanesulfonate on a DB-5 (30 m×0.32 mm×1.0 μm) capillary column under programming temperature. Acetonitrile, water and ammonia (90:9:1 v/v/v) mixture was used as diluent. Various factors involved in the gas chromatography-mass 

spectrometry method development are also presented. This method was validated as per International Conference on Harmonization guidelines. The limit of quantitation of methyl methanesulfonate, ethyl methanesulfonate, isopropyl methanesulfonate and n-butyl methanesulfonate is 6 ppm with respect to 30 mg/ml of doxazosin mesylate.

 

2. J. Braz. Chem. Soc., 19, 427(2008); Schrekker,H., et al.
3. Phys.Chem. Chem. Phys., 11, 8939(2009); Blesic, M., et al.