BVT-14225

For research use only. Not for therapeutic Use.

  • CAT Number: I004564
  • CAS Number: 376638-65-2
  • Molecular Formula: C16H20ClN3O3S2
  • Molecular Weight: 401.924
  • Purity: ≥95%
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BVT-14225(CAT: I004564) represents a significant compound in the domain of pharmaceutical and medicinal chemistry. Functioning as an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), BVT-14225 holds promise for modulating glucocorticoid metabolism. By targeting 11β-HSD1, an enzyme involved in the interconversion of active and inactive glucocorticoids, BVT-14225 may contribute to therapeutic strategies targeting conditions influenced by glucocorticoid excess or deficiency. This includes potential applications in metabolic disorders, immune-related diseases, and inflammatory conditions.


Catalog Number I004564
CAS Number 376638-65-2
Synonyms

BVT-14225; BVT 14225; BVT14225.;2-(2-((3-chloro-2-methylphenyl)sulfonamido)thiazol-4-yl)-N,N-diethylacetamide

Molecular Formula C16H20ClN3O3S2
Purity ≥95%
Target 11β-HSD
Solubility Soluble in DMSO
Storage 0 - 4 °C for short term or -20 °C for long term
InChI InChI=1S/C16H20ClN3O3S2/c1-4-20(5-2)15(21)9-12-10-24-16(18-12)19-25(22,23)14-8-6-7-13(17)11(14)3/h6-8,10H,4-5,9H2,1-3H3,(H,18,19)
InChIKey PNFMZAHWOASGJC-UHFFFAOYSA-N
SMILES O=C(N(CC)CC)CC1=CSC(NS(=O)(C2=CC=CC(Cl)=C2C)=O)=N1
Reference

</br>1: Yoo HH, Kim NS, Kim MJ, Shin D, Shin JG, Kim DH. Enantioselective carbonyl</br> reduction of eperisone in human liver microsomes. Xenobiotica. 2011</br> Sep;41(9):758-63. doi: 10.3109/00498254.2011.576277. PubMed PMID: 216237

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