For research use only. Not for therapeutic Use.
BW-723C86 is a potent and a selective 5-HT2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats[1][2][3].
| Catalog Number | I011868 |
| CAS Number | 160521-72-2 |
| Synonyms | 1-[5-(thiophen-2-ylmethoxy)-1H-indol-3-yl]propan-2-amine;hydrochloride |
| Molecular Formula | C16H19ClN2OS |
| Purity | ≥95% |
| InChI | InChI=1S/C16H18N2OS.ClH/c1-11(17)7-12-9-18-16-5-4-13(8-15(12)16)19-10-14-3-2-6-20-14;/h2-6,8-9,11,18H,7,10,17H2,1H3;1H |
| InChIKey | PYJBJMIBANAOFJ-UHFFFAOYSA-N |
| SMILES | CC(CC1=CNC2=C1C=C(C=C2)OCC3=CC=CS3)N.Cl |
| Reference | [1]. Kennett GA, et, al. BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats. Neuropharmacology. 1997 Feb;36(2):233-9. [2]. Kennett GA, et, al. Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated. Neuropharmacology. 1998 Dec;37(12):1603-10. [3]. Matsumoto T, et, al. Effect of Equol on Vasocontractions in Rat Carotid Arteries Treated with High Insulin. Biol Pharm Bull. 2019;42(6):1048-1053. |
