c-Fms-IN-13

• CAT Number: I042756
• CAS Number: 885704-58-5
• Molecular Formula: C22H26N4O2
• Molecular Weight: 378.47
• Purity: ≥95%
• Synonyms: 5-cyano-N-[2,4-di(piperidin-1-yl)phenyl]furan-2-carboxamide
• InChI: InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-9-7-17(25-11-3-1-4-12-25)15-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27)
• InChIKey: QSPUWGIYPBXIJO-UHFFFAOYSA-N
• SMILES: C1CCN(CC1)C2=CC(=C(C=C2)NC(=O)C3=CC=C(O3)C#N)N4CCCCC4

c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent[1].

Reference

[1]. Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8.
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