For research use only. Not for therapeutic Use.
C-2 dihydro-Ceramide is a metabolically inactive analog of C-2 ceramide (Item No. <span class=/itemid/>62510</span>), It is used as a negative control in experiments investigating the biological activity of C-2 ceramide.
| Catalog Number | R020633 |
| CAS Number | 13031-64-6 |
| Synonyms | N-[(1S,2R)-2-Hydroxy-1-(hydroxymethyl)heptadecyl]acetamide; D-erythro-1,3-Dihydroxy-2-acetamidooctadecane; D-erythro-2-Acetamido-1,3-octadecanediol; D-erythro-C2-Dihydroceramide; N-Acetyldihydrosphingosine; N-Acetylsphinganine |
| Molecular Formula | C20H41NO3 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]acetamide |
| InChI | InChI=1S/C20H41NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(24)19(17-22)21-18(2)23/h19-20,22,24H,3-17H2,1-2H3,(H,21,23)/t19-,20+/m0/s1 |
| InChIKey | CRJGESKKUOMBCT-VQTJNVASSA-N |
| SMILES | CCCCCCCCCCCCCCCC(C(CO)NC(=O)C)O |
| Reference | <br>1. F. Bi et al. “A Conserved Cysteine Motif Is Critical for Rice Ceramide Kinase Activity and Function” PLoS ONE 6(3): e18079.doi:10.1371/journal.pone.0018079, 2011<br>2. L. Siskind et al. “Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations” Mitochondrion, vol. 6 pp. 118-125, 2006<br>3. T. Goldkorn et al. “H2O2 acts on cellular membranes to generate ceramide signaling and initiate apoptosis in tracheobronchial epithelial cells” Journal ofCell Science, vol. 111 pp. 3209-3220, 1998<br>4. W. Zheng “Fenretinide increases dihydroceramide and dihydrosphingolipids due to inhibition of dihydroceramide desaturase” Georgia Institute ofTechnology, 2006</br></br></br></br> |
