For research use only. Not for therapeutic Use.
C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes[1].
| Catalog Number | I041128 |
| CAS Number | 27888-44-4 |
| Synonyms | N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]docosanamide |
| Molecular Formula | C40H79NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C40H79NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-24-26-28-30-32-34-36-40(44)41-38(37-42)39(43)35-33-31-29-27-25-23-16-14-12-10-8-6-4-2/h33,35,38-39,42-43H,3-32,34,36-37H2,1-2H3,(H,41,44)/b35-33+/t38-,39+/m0/s1 |
| InChIKey | KEPQASGDXIEOIL-GLQCRSEXSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCCCCC(=O)NC(CO)C(C=CCCCCCCCCCCCCC)O |
| Reference | [1]. Stiban J, et al. Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis. Biochim Biophys Acta. 2015 Feb;1848(2):561-7. |
