For research use only. Not for therapeutic Use.
C3a (70-77)(CAT: I020198) is an octapeptide fragment corresponding to the C-terminal region of the complement component C3a, specifically amino acids 70 to 77. This peptide retains the specificity of native C3a but exhibits only 1–2% of its full biological activity. C3a is a key player in the complement system, functioning as an anaphylatoxin that promotes inflammation, immune cell recruitment, and histamine release from mast cells and basophils. Due to its reduced activity, C3a (70-77) is used in immunology research to study complement-mediated immune responses and to explore the modulation of inflammatory processes without triggering full immune activation.
| CAS Number | 63555-63-5 |
| Molecular Formula | C₃₅H₆₁N₁₃O₁₀ |
| Purity | ≥95% |
| Target | Complement System |
| IUPAC Name | 2-[2-[[2-[[2-[[2-[[2-[[2-(2-aminopropanoylamino)-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]propanoylamino]-5-(diaminomethylideneamino)pentanoic acid |
| InChI | InChI=1S/C35H61N13O10/c1-17(2)10-23(46-32(55)25(12-21-13-39-16-42-21)47-33(56)26(15-49)48-28(51)19(5)36)30(53)41-14-27(50)44-24(11-18(3)4)31(54)43-20(6)29(52)45-22(34(57)58)8-7-9-40-35(37)38/h13,16-20,22-26,49H,7-12,14-15,36H2,1-6H3,(H,39,42)(H,41,53)(H,43,54)(H,44,50)(H,45,52)(H,46,55)(H,47,56)(H,48,51)(H,57,58)(H4,37,38,40) |
| InChIKey | LYTNSBOBASKUDN-UHFFFAOYSA-N |
| SMILES | CC(C)CC(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC1=CN=CN1)NC(=O)C(CO)NC(=O)C(C)N |
