For research use only. Not for therapeutic Use.
C75(CAT: I002666) is a potent fatty acid synthase (FASN) inhibitor with significant applications in metabolic and oncology research. It exhibits an IC₅₀ of 35.4 μM for inhibiting proliferation in LNCaP prostate cancer cells, highlighting its role in targeting lipid metabolism. By blocking FASN, C75 disrupts fatty acid biosynthesis, which is critical for tumor growth and survival, particularly in cancer cells with high metabolic demands. Additionally, it aids in studying metabolic disorders, obesity, and the interplay between lipid metabolism and cell signaling. C75 is a valuable tool for exploring FASN as a therapeutic target in cancer and metabolic disease research.
Catalog Number | I002666 |
CAS Number | 218137-86-1 |
Molecular Formula | C14H22O4 |
Purity | ≥95% |
Target | Fatty Acid Synthase (FASN) |
Solubility | DMSO: 5 mg/mL; |
Storage | Store at +4C |
IC50 | 35.4 μM(LNCaP cel) [1] |
IUPAC Name | 4-methylidene-2-octyl-5-oxooxolane-3-carboxylic acid |
InChI | InChI=1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16) |
InChIKey | VCWLZDVWHQVAJU-UHFFFAOYSA-N |
SMILES | CCCCCCCCC1C(C(=C)C(=O)O1)C(=O)O |