CA-170 (AUPM-170)

• CAT Number: I013725
• CAS Number: 1673534-76-3
• Molecular Formula: C12H20N6O7
• Molecular Weight: 360.32
• Purity: ≥95%

CA-170 (AUPM-170, PD-1-IN-1 ) is potent and orally available inhibitor of the immune checkpoint regulatory proteins PD-L1 (programmed cell death ligand-1) and VISTA (V-domain immunoglobulin (Ig) suppressor of T-cell activation). CA-170 exhibits anti-tumor efficacy.

Reference

[1] Musielak B, et al. Molecules. 2019 Aug 1;24(15):2804.
[2] Sasikumar PG, et al. Commun Biol. 2021 Jun 8;4(1):699.