Ca2+ channel agonist 1

• CAT Number: I001538
• CAS Number: 1402821-24-2
• Molecular Formula: C19H26N6O
• Molecular Weight: 354.45
• Purity: ≥95%
• Target: Calcium Channel, CDK
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IC50: 14.23 uM (EC50, Ca2+ channel) 3.34 uM (EC50, cdk2)
• IUPAC Name: (2R)-2-[[6-(benzylamino)-9-propylpurin-2-yl]amino]butan-1-ol
• InChI: InChI=1S/C19H26N6O/c1-3-10-25-13-21-16-17(20-11-14-8-6-5-7-9-14)23-19(24-18(16)25)22-15(4-2)12-26/h5-9,13,15,26H,3-4,10-12H2,1-2H3,(H2,20,22,23,24)/t15-/m1/s1
• InChIKey: LKXPLOHGQSEPEM-OAHLLOKOSA-N
• SMILES: CCCN1C=NC2=C(N=C(N=C21)NC(CC)CO)NCC3=CC=CC=C3

Ca2+ channel agonist 1 (Cat No.: I001538) is an N-type Ca2+ channel agonist and Cdk2 inhibitor, with EC50 of 14.23 μM and 3.34 μM, respectively. potentially curative. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.

Reference

[1]. Liang M, et al. Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist. ACS Med Chem Lett. 2012 Oct 1;3(12):985-990.