Cabazitaxel-C13

• CAT Number: I005395
• CAS Number: N/A
• Molecular Formula: C45H51D6NO14
• Molecular Weight: 841.97
• Purity: ≥95%
• Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-di(methoxy-13C)-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocycl
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• SMILES: O=C(C1=CC=CC=C1)O[C@H]([C@@]2(C[C@@H](C(C)=C([C@H](C3=O)O[13CH3])C2(C)C)OC([C@@H]([C@H](C4=CC=CC=C4)NC(OC(C)(C)C)=O)O)=O)O)[C@]5([C@]3([C@H](C[C@H]6OC[C@]65OC(C)=O)O[13CH3])C)[H]

Cabazitaxel-C13(CAT: I005395) is a labeled derivative of cabazitaxel, a next-generation taxane chemotherapeutic agent used in cancer treatment. This compound is modified with a carbon-13 isotope, making it particularly valuable for pharmacokinetic and metabolic research. By incorporating the stable isotope, Cabazitaxel-C13 enables precise tracing of drug metabolism, distribution, and clearance in biological systems. Its primary application lies in studying the behavior of cabazitaxel in cancer models, enhancing the understanding of its efficacy and safety profiles. This isotopically labeled compound is an essential tool for advancing drug development and optimizing taxane-based therapies for resistant and metastatic cancers.