For research use only. Not for therapeutic Use.
Cadralazine (CAT: I009485) is a compound recognized for its pharmacological properties as a peripheral arteriolar vasodilator and an antihypertensive agent. It exerts its effects by relaxing the smooth muscle in peripheral arterioles, leading to dilation and consequent reduction in blood pressure. Cadralazine’s vasodilatory action contributes to improved blood flow and decreased vascular resistance, ultimately aiding in the management of hypertension.
| Catalog Number | I009485 |
| CAS Number | 64241-34-5 |
| Synonyms | Cadralazine; ISF-2469; ISF 2469; ISF2469;;Ethyl N-[[6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl]amino]carbamate |
| Molecular Formula | C12H21N5O3 |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | Store at 0-8 °C |
| IUPAC Name | ethyl N-[[6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl]amino]carbamate |
| InChI | InChI=1S/C12H21N5O3/c1-4-17(8-9(3)18)11-7-6-10(13-15-11)14-16-12(19)20-5-2/h6-7,9,18H,4-5,8H2,1-3H3,(H,13,14)(H,16,19) |
| InChIKey | QLTVVOATEHFXLT-UHFFFAOYSA-N |
| SMILES | CCN(CC(C)O)C1=NN=C(C=C1)NNC(=O)OCC |
| Reference | </br>1: Ebihara A, Fujimura A. Metabolites of antihypertensive drugs. An updated review of their clinical pharmacokinetic and therapeutic implications. Clin Pharmacokinet. 1991 Nov;21(5):331-43. Review. PubMed PMID: 1773548.</br>2: McTavish D, Young RA, Clissold SP. Cadralazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension. Drugs. 1990 Oct;40(4):543-60. Review. PubMed PMID: 2083513.</br></br> |
