Caffeic Acid Phenethyl Ester

• CAT Number: R002164
• CAS Number: 104594-70-9
• Molecular Formula: C17H16O4
• Molecular Weight: 284.3
• Purity: ≥95%
• Synonyms: 3-(3,4-Dihydroxyphenyl)-2-propenoic Acid 2-Phenylethyl Ester; CAPE; Phenethyl Caffeate
• Target: NF-κB
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at -20 ℃
• InChI: InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
• InChIKey: SWUARLUWKZWEBQ-VQHVLOKHSA-N
• SMILES: C1=CC=C(C=C1)CCOC(=O)/C=C/C2=CC(=C(C=C2)O)O

Caffeic Acid Phenethyl Ester (CAPE) is a bioactive compound derived from propolis, widely studied for its anti-inflammatory, antioxidant, and anticancer properties. It inhibits the activation of nuclear factor-kappa B (NF-κB), making it a valuable tool in exploring pathways involved in inflammation and immune response. CAPE has also shown potential in protecting cells from oxidative stress and reducing tumor growth in various cancer models. Its versatility makes it a critical molecule in biomedical research, particularly for studies on cancer, neurodegenerative diseases, and cardiovascular disorders, contributing to the development of novel therapeutic strategies.