For research use only. Not for therapeutic Use.
<p>It is a CNS stimulant.</p><br />Alkaloid,<!–C<SUB>8</SUB>H<SUB>10</SUB>N<SUB>4</SUB>O<SUB>2</SUB>–>purified from plants of <I>Coffea genus</i>, Rubiaceae.</br><p>A1 adenosine receptor: Ki = 29 &mu;M; A<sub>2</sub> adenosine receptor: Ki = 48 &mu;M<br /><br />It is a Ca<sup>2+</sup> channels activator and so an agonist of <strong>Ryanodine </strong>receptors.</p></br>
| Catalog Number | R009245 |
| CAS Number | 58-08-2 |
| Synonyms | 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; 1,3,7-Trimethylxanthine; 7-Methyltheophylline; Alert-Pep; Cafalgine; Cafeina; Caffedrine; Caffein; Cafipel; DHCplus; Dasin; Diurex; Durvitan; Guaranine; Hycomine; Koffein; Mateina; Methyltheobromine; M |
| Molecular Formula | C8H10N4O2 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 1,3,7-trimethylpurine-2,6-dione |
| InChI | InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3 |
| InChIKey | RYYVLZVUVIJVGH-UHFFFAOYSA-N |
| SMILES | CN1C=NC2=C1C(=O)N(C(=O)N2C)C |
| Reference | – Zubair et al., /Analytical profiles of drug substances/, <I>Florey Ed., Academic Press</I>, New York, (1986). 15:71-150<br /><br />- Saano et al.; Acta Pharmacol et toxicol. (1982). 51:300<br /><br />- Bruns et al., Mol. Pharmacol. (1986). 29:331<br /><br />- Pessah et al., <I>Mol. Pharmacol</I>. (1987). 31:232-238<br /><br /><br /><br /> |
