For research use only. Not for therapeutic Use.
Caficrestat (Aldose reductase-IN-1) is a inhibitor of aldose reductase with IC50 of 28.9 pM[1].
| Catalog Number | I001376 |
| CAS Number | 1355612-71-3 |
| Synonyms | 2-[5-oxo-6-[[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl]pyrazino[2,3-d]pyridazin-8-yl]acetic acid |
| Molecular Formula | C17H10F3N5O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H10F3N5O3S/c18-17(19,20)8-1-2-11-9(5-8)23-12(29-11)7-25-16(28)15-14(21-3-4-22-15)10(24-25)6-13(26)27/h1-5H,6-7H2,(H,26,27) |
| InChIKey | YRGPAXAVTDMKDK-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1C(F)(F)F)N=C(S2)CN3C(=O)C4=NC=CN=C4C(=N3)CC(=O)O |
| Reference | [1]. ALDOSE REDUCTASE INHIBITORS AND USES THEREOF |
