'CAGED GTP

• CAT Number: M113522
• CAS Number: 125455-57-4
• Molecular Formula: C18H21N6Na2O16P3
• Molecular Weight: 716.293
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: disodium;[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [hydroxy-[1-(2-nitrophenyl)ethoxy]phosphoryl] phosphate
• InChI: InChI=1S/C18H23N6O16P3.2Na/c1-8(9-4-2-3-5-10(9)24(28)29)38-42(32,33)40-43(34,35)39-41(30,31)36-6-11-13(25)14(26)17(37-11)23-7-20-12-15(23)21-18(19)22-16(12)27;;/h2-5,7-8,11,13-14,17,25-26H,6H2,1H3,(H,30,31)(H,32,33)(H,34,35)(H3,19,21,22,27);;/q;2*+1/p-2/t8?,11-,13-,14-,17-;;/m1../s1
• InChIKey: CALBQCHIEXMHHD-UFPGFHDMSA-L
• SMILES: CC(C1=CC=CC=C1[N+](=O)[O-])OP(=O)(O)OP(=O)([O-])OP(=O)([O-])OCC2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)N)O)O.[Na+].[Na+]

'CAGED GTP(CAS 125455-57-4) is a photolabile derivative of GTP. Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage producing a concentration jump of GTP.

Reference

1.Schlichting, Ilme, et al. "Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis." Proceedings of the National Academy of Sciences 86.20 (1989): 7687-7690.