Calcium Channel antagonist 2

• CAT Number: I040681
• CAS Number: 874370-15-7
• Molecular Formula: C23H25FN2O4S
• Molecular Weight: 444.52
• Purity: ≥95%
• Synonyms: N-[(4-fluorophenyl)methyl]-3-methyl-5-(4-methylpiperidin-1-yl)sulfonyl-1-benzofuran-2-carboxamide
• InChI: InChI=1S/C23H25FN2O4S/c1-15-9-11-26(12-10-15)31(28,29)19-7-8-21-20(13-19)16(2)22(30-21)23(27)25-14-17-3-5-18(24)6-4-17/h3-8,13,15H,9-12,14H2,1-2H3,(H,25,27)
• InChIKey: JMKMEDRXKRPMHV-UHFFFAOYSA-N
• SMILES: CC1CCN(CC1)S(=O)(=O)C2=CC3=C(C=C2)OC(=C3C)C(=O)NCC4=CC=C(C=C4)F

Calcium Channel antagonist 2 (Compound 154) is a calcium channel antagonist (IC50=5-20 μM). Calcium Channel antagonist 2 can be used in study of calcium channel-mediated diseases such as pain and diabetes[1].

Reference

[1]. Andreas P Termin, et al. Heterocyclic derivatives for modulation of calcium channels. Patent WO2006010008A1.