For research use only. Not for therapeutic Use.
Calcium Channel Antagonist 3 (Cat No.: I040680) is a small-molecule inhibitor designed to block voltage-gated calcium channels (VGCCs), particularly L-type or T-type subtypes, which are involved in calcium influx in excitable cells. By inhibiting these channels, the compound reduces intracellular calcium levels, leading to decreased smooth muscle contraction, neurotransmitter release, and cardiac workload. It is used in preclinical research to study calcium-dependent signaling in cardiovascular, neurological, and pain-related disorders, with potential therapeutic applications in hypertension, arrhythmias, and neuropathic pain.
| CAS Number | 687573-14-4 |
| Synonyms | N-benzyl-3-methyl-5-(3-methylpiperidin-1-yl)sulfonyl-1-benzofuran-2-carboxamide |
| Molecular Formula | C23H26N2O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C23H26N2O4S/c1-16-7-6-12-25(15-16)30(27,28)19-10-11-21-20(13-19)17(2)22(29-21)23(26)24-14-18-8-4-3-5-9-18/h3-5,8-11,13,16H,6-7,12,14-15H2,1-2H3,(H,24,26) |
| InChIKey | JPAQHVPMJBXAMI-UHFFFAOYSA-N |
| SMILES | CC1CCCN(C1)S(=O)(=O)C2=CC3=C(C=C2)OC(=C3C)C(=O)NCC4=CC=CC=C4 |
| Reference | [1]. Termin, Andreas P, et, al. Benzofuran, indole and benzothiophene sulfonamide calcium channel antagonists for treating pain. WO2006010008 A1 2006-01-26. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
