Calmidazolium (cation)

• CAT Number: I023980
• CAS Number: 95013-41-5
• Molecular Formula: C31H23Cl6N2O+
• Molecular Weight: 652.24
• Purity: 98%
• Synonyms: Calmidazolium (cation); R24571; R 24571; R-24571
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazol-3-ium
• InChI: InChI=1S/C31H23Cl6N2O/c32-23-6-1-20(2-7-23)31(21-3-8-24(33)9-4-21)39-14-13-38(19-39)17-30(27-12-11-26(35)16-29(27)37)40-18-22-5-10-25(34)15-28(22)36/h1-16,19,30-31H,17-18H2/q+1
• InChIKey: CTKNMSVWMRRCPW-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)N3C=C[N+](=C3)CC(C4=C(C=C(C=C4)Cl)Cl)OCC5=C(C=C(C=C5)Cl)Cl)Cl

Calmidazolium(CAT: I023980) is a potent calmodulin antagonist that inhibits calmodulin-dependent enzymes by binding to the calmodulin protein, interfering with calcium signaling pathways. This compound is widely used in research to investigate the role of calmodulin in various physiological processes, such as muscle contraction, cell proliferation, and neurotransmitter release. By modulating calmodulin activity, Calmidazolium provides insights into calcium-mediated signaling and its implications in pathological conditions, including cancer, cardiovascular diseases, and neurodegenerative disorders. Its high specificity and efficacy make it an invaluable tool for studying calcium-calmodulin interactions and developing calmodulin-targeted therapeutic strategies.