For research use only. Not for therapeutic Use.
Calycanthine(CAT: I018418) is a naturally occurring bisindole alkaloid derived from plants of the Calycanthaceae family, widely studied for its unique chemical structure and biological activity. It is known for its neurotoxic and convulsant properties, acting as a potent antagonist of glycine receptors, which play a critical role in inhibitory neurotransmission in the central nervous system. Calycanthine is commonly used in neuropharmacological research to explore mechanisms of synaptic transmission, receptor modulation, and excitotoxicity. With its distinctive molecular framework, it also serves as a scaffold for synthetic derivatives in drug discovery. Calycanthine is a valuable tool for advancing research in neurobiology and medicinal chemistry.
| Catalog Number | I018418 |
| CAS Number | 595-05-1 |
| Molecular Formula | C₂₂H₂₆N₄ |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| IUPAC Name | (1S,2R,10S,11R)-21,24-dimethyl-3,12,21,24-tetrazahexacyclo[9.7.3.32,10.01,10.04,9.013,18]tetracosa-4,6,8,13,15,17-hexaene |
| InChI | InChI=1S/C22H26N4/c1-25-13-11-22-16-8-4-5-9-17(16)23-19(25)21(22)12-14-26(2)20(22)24-18-10-6-3-7-15(18)21/h3-10,19-20,23-24H,11-14H2,1-2H3/t19-,20-,21-,22-/m1/s1 |
| InChIKey | XSYCDVWYEVUDKQ-GXRSIYKFSA-N |
| SMILES | CN1CC[C@@]23[C@@H]4NC5=CC=CC=C5[C@@]2([C@@H]1NC6=CC=CC=C36)CCN4C |
