cAMPS-Sp, triethylammonium salt

• CAT Number: I011492
• CAS Number: 73208-40-9
• Molecular Formula: C16H27N6O5PS
• Molecular Weight: 446.463
• Purity: ≥95%
• Synonyms: (2S,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-sulfide compound with triethylamine (1:1)
• Target: TGF-beta/Smad
• Solubility: Soluble to 100 mM in sterile water
• Storage: Store at -20°C
• IUPAC Name: (4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol;N,N-diethylethanamine
• InChI: InChI=1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/t4-,6-,7-,10-,21?;/m1./s1
• InChIKey: OXIPZMKSNMRTIV-NVGWRVNNSA-N
• SMILES: CCN(CC)CC.C1C2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)OP(=S)(O1)O

cAMPS-Sp, triethylammonium salt(CAT: I011492) is a cyclic AMP (cAMP) analog that has been widely used as a tool in biochemical and pharmacological research to study cAMP-dependent signaling pathways. It is a cell-permeable derivative of cAMP that can activate cAMP-dependent protein kinase (PKA) and stimulate downstream signaling events. The triethylammonium salt form of cAMPS-Sp is often used for its enhanced solubility and stability in aqueous solutions.