For research use only. Not for therapeutic Use.
Cantharidin (Cat No.: I004099) is a naturally occurring terpenoid toxin produced by blister beetles, particularly Lytta vesicatoria. It inhibits protein phosphatases 1 and 2A, disrupting cellular signaling and inducing apoptosis. Historically used as a vesicant and in traditional medicine, cantharidin is now applied clinically in dermatology to treat warts and molluscum contagiosum due to its ability to cause controlled blistering. Despite its therapeutic potential, cantharidin is highly toxic if ingested and must be used with caution under medical supervision in topical applications.
| CAS Number | 56-25-7 |
| Synonyms | NSC 61805 |
| Molecular Formula | C₁₀H₁₂O₄ |
| Purity | ≥95% |
| Solubility | 10 mM in DMSO |
| Storage | 4°C |
| InChI | InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10- |
| InChIKey | DHZBEENLJMYSHQ-XCVPVQRUSA-N |
| SMILES | CC12C3CCC(C1(C(=O)OC2=O)C)O3 |
| Reference | <p style=/line-height:25px/> <br>[2]. Huang Z, et al. Lethal and Sublethal Effects of Cantharidin on Development and Reproduction of Plutella xylostella (Lepidoptera: Plutellidae). J Econ Entomol. 2015 Jun;108(3):1054-64. <br>[3]. Shen M, et al. Cantharidin represses invasion of pancreatic cancer cells through accelerated degradation of MMP2 mRNA. Sci Rep. 2015 Jul 2;5:11836. </p> |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
