For research use only. Not for therapeutic Use.
CAP-7.1 is a DNA topoisomerase inhibitor potentially for the treatment of biliary cancer and non-small cell lung cancer
| Catalog Number | I005539 |
| CAS Number | 433304-61-1 |
| Synonyms | CAP-7.1; CAP7.1; CAP 7.1;4-((5R,5aR,8aR,9S)-9-(((4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-6-oxo-5,5a,6,8,8a,9-hexahydrofuro[3/’,4/’:6,7]naphtho[2,3-d][1,3]dioxol-5-yl)-2,6-dimethoxyphenyl ((2,2-dimethyl-1,3- |
| Molecular Formula | C36H42O17 |
| Purity | ≥95% |
| Target | DNA topoisomerase inhibitor |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| IUPAC Name | [4-[(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-9-yl]-2,6-dimethoxyphenyl] (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate |
| InChI | InChI=1S/C36H42O17/c1-15-43-13-25-32(49-15)28(37)29(38)34(50-25)51-30-19-9-22-21(46-14-47-22)8-18(19)26(27-20(30)12-44-33(27)39)16-6-23(41-4)31(24(7-16)42-5)52-35(40)45-10-17-11-48-36(2,3)53-17/h6-9,15,17,20,25-30,32,34,37-38H,10-14H2,1-5H3/t15-,17?,20+,25-,26-,27+,28-,29-,30-,32-,34+/m1/s1 |
| InChIKey | FCWSQAKOPTZCOD-SQYSSJHTSA-N |
| SMILES | CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)OC(=O)OCC8COC(O8)(C)C)OC)O)O |
| Reference | </br>1: Ben-Chaim A, Borovsky Y, Falise M, Mazourek M, Kang BC, Paran I, Jahn M. QTL analysis for capsaicinoid content in Capsicum. Theor Appl Genet.</br> 2006 Nov;113(8):1481-90. PubMed PMID: 16960715. |
