CAP-7.1

• CAT Number: I005539
• CAS Number: 433304-61-1
• Molecular Formula: C36H42O17
• Molecular Weight: 746.72
• Purity: ≥95%
• Synonyms: CAP-7.1; CAP7.1; CAP 7.1;4-((5R,5aR,8aR,9S)-9-(((4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-6-oxo-5,5a,6,8,8a,9-hexahydrofuro[3/’,4/’:6,7]naphtho[2,3-d][1,3]dioxol-5-yl)-2,6-dimethoxyphenyl ((2,2-dimethyl-1,3-
• Target: DNA topoisomerase inhibitor
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: [4-[(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-9-yl]-2,6-dimethoxyphenyl] (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate
• InChI: InChI=1S/C36H42O17/c1-15-43-13-25-32(49-15)28(37)29(38)34(50-25)51-30-19-9-22-21(46-14-47-22)8-18(19)26(27-20(30)12-44-33(27)39)16-6-23(41-4)31(24(7-16)42-5)52-35(40)45-10-17-11-48-36(2,3)53-17/h6-9,15,17,20,25-30,32,34,37-38H,10-14H2,1-5H3/t15-,17?,20+,25-,26-,27+,28-,29-,30-,32-,34+/m1/s1
• InChIKey: FCWSQAKOPTZCOD-SQYSSJHTSA-N
• SMILES: C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)OC(=O)OCC8COC(O8)(C)C)OC)O)O

CAP-7.1（Cat No.:I005539）is a small molecule inhibitor targeting the protein kinase C (PKC) pathway, a key regulator of various cellular processes, including cell growth, differentiation, and apoptosis. PKC is implicated in the development and progression of several cancers, including breast, prostate, and lung cancers. By inhibiting PKC, CAP-7.1 aims to disrupt cancer cell signaling, inhibit tumor growth, and reduce metastasis. Preclinical studies have shown promise in targeting PKC in cancer therapy, though further clinical research is necessary to evaluate CAP-7.1’s safety, efficacy, and therapeutic potential as an anticancer agent.

Reference

1: Ben-Chaim A, Borovsky Y, Falise M, Mazourek M, Kang BC, Paran I, Jahn M. QTL analysis for capsaicinoid content in Capsicum. Theor Appl Genet. 2006 Nov;113(8):1481-90. PubMed PMID: 16960715.