Capecitabine-d11

• CAT Number: S000421
• CAS Number: 1132662-08-8
• Molecular Formula: C15H11D11FN3O6
• Molecular Weight: 370.42
• Purity: ≥95%
• IUPAC Name: 1,1,2,2,3,3,4,4,5,5,5-undecadeuteriopentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate
• InChI: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1/i1D3,3D2,4D2,5D2,6D2
• InChIKey: GAGWJHPBXLXJQN-XSFNBKHLSA-N
• SMILES: CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O

Capecitabine-d11（Cat No.:S000421） is a deuterated version of capecitabine, where eleven hydrogen atoms are replaced with deuterium. This structural modification enhances the drug’s metabolic stability and is used in detailed pharmacokinetic and metabolic research. Capecitabine is an oral chemotherapeutic agent metabolized in the body to 5-fluorouracil (5-FU), inhibiting DNA synthesis in cancer cells, thus stopping their growth. The deuterated version, Capecitabine-d11, allows for a more precise analysis of the drug’s absorption, metabolism, and excretion, helping researchers better understand its efficacy and safety profile in cancer treatment.