For research use only. Not for therapeutic Use.
Capreomycin sulfate（Cat No.:I001559）is an injectable antibiotic used primarily to treat multidrug-resistant tuberculosis (MDR-TB). It belongs to the class of polypeptide antibiotics and is derived from the bacterium Streptomyces capreolus. Capreomycin works by inhibiting protein synthesis in mycobacteria, effectively stopping bacterial growth. It’s often used in combination with other anti-TB drugs to enhance treatment efficacy and prevent resistance. Due to potential side effects, including nephrotoxicity and ototoxicity, its use is generally reserved for cases where other treatments have failed. Capreomycin sulfate remains an important option in TB management worldwide.
| Catalog Number | I001559 |
| CAS Number | 1405-37-4 |
| Synonyms | (2S)-2,5-diamino-N-(((2S,5R,11S,15R,Z)-15-amino-11-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-5-yl)methyl)pentanamide, monosulfate |
| Molecular Formula | C24H42N14O8 • H2SO4 |
| Purity | 99% |
| Solubility | H2O: ≥ 37 mg/mL |
| Appearance | White solid |
| Storage | -20°C |
| Analysis method | HPLC |
| IUPAC Name | (2S)-2,5-diamino-N-[[(5S,8Z,15S)-15-amino-11-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-8-[(carbamoylamino)methylidene]-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-1,4,7,10,13-pentazacyclohexadec-5-yl]methyl]pentanamide;sulfuric acid |
| InChI | InChI=1S/C24H42N14O8.H2O4S/c25-4-1-2-10(26)17(40)32-7-13-19(42)34-14(8-33-24(29)46)20(43)38-16(12-3-5-30-23(28)37-12)22(45)31-6-11(27)18(41)36-15(9-39)21(44)35-13;1-5(2,3)4/h8,10-13,15-16,39H,1-7,9,25-27H2,(H,31,45)(H,32,40)(H,34,42)(H,35,44)(H,36,41)(H,38,43)(H3,28,30,37)(H3,29,33,46);(H2,1,2,3,4)/b14-8-;/t10-,11-,12?,13-,15?,16?;/m0./s1 |
| InChIKey | LFFNIXQXRKNZCE-BSPPLRILSA-N |
| SMILES | C1CN=C(NC1C2C(=O)NC[C@@H](C(=O)NC(C(=O)N[C@H](C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CNC(=O)[C@H](CCCN)N)CO)N)N.OS(=O)(=O)O |
| Reference | <p style=”/line-height:25px/”> |
