For research use only. Not for therapeutic Use.
An efficacious therapeutic indicated in Alzheimer’s disease (AD); clearing β-amyloid plaque in-vivo; restoring memory in rats
| Catalog Number | I004907 |
| CAS Number | 4952-56-1 |
| Molecular Formula | C33H52O4 |
| Purity | ≥95% |
| IUPAC Name | [(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl] hexanoate |
| InChI | InChI=1S/C33H52O4/c1-6-7-8-9-29(34)36-24-13-15-31(4)23(18-24)10-11-25-26(31)14-16-32(5)27(25)19-28-30(32)22(3)33(37-28)17-12-21(2)20-35-33/h10,21-22,24-28,30H,6-9,11-20H2,1-5H3/t21-,22+,24+,25-,26+,27+,28+,30+,31+,32+,33-/m1/s1 |
| SMILES | CCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)C[C@H]5[C@@H]4[C@@H]([C@]6(O5)CC[C@H](CO6)C)C)C)C |
| Reference | L Lecanu et al. Caprospinol reduces amyloid deposits and improves cognitive function in a rat model of Alzheimer’s disease. Neurosci. 2010, 165(2), 427-35.
L Lecanu et al. Caprospinol: moving from a neuroactive steroid to a neurotropic drug. Exp. Opin. Invest. Drugs, 2009, 18(3), 265-276(12). |
