Captopril-d3

• CAT Number: R007569
• CAS Number: 1356383-38-4
• Molecular Formula: C₉H₁₂D₃NO₃S
• Molecular Weight: 220.3
• Purity: ≥95%
• Synonyms: (2S)-1-(3-Marcapto-2-methyl-1-oxopionyl]-L-proline-2,5,5-d3;?SQ-14225-d3
• Storage: Store at -20°C
• IUPAC Name: (2S)-2,5,5-trideuterio-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
• InChI: InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1/i4D2,7D
• InChIKey: FAKRSMQSSFJEIM-SIHDFBQLSA-N
• SMILES: [2H][C@]1(CCC(N1C(=O)[C@H](C)CS)([2H])[2H])C(=O)O

Captopril-d3 is a deuterated form of Captopril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and heart failure. The deuterium labeling in Captopril-d3 allows for detailed pharmacokinetic and metabolic studies, as it facilitates the tracing and quantification of the drug in biological systems. This compound is particularly useful in pharmaceutical research to understand the drug’s metabolic pathways, bioavailability, and excretion. In organic chemistry, Captopril-d3 aids in the development and refinement of analytical techniques, contributing to the optimization of ACE inhibitors and other related therapeutic agents.