Carazolol

• CAT Number: I011427
• CAS Number: 57775-29-8
• Molecular Formula: C18H22N2O2
• Molecular Weight: 298.38
• Purity: ≥95%
• Synonyms: 1-(9H-carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
• InChI: InChI=1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3
• InChIKey: BQXQGZPYHWWCEB-UHFFFAOYSA-N
• SMILES: CC(C)NCC(COC1=CC=CC2=C1C3=CC=CC=C3N2)O

Carazolol is a β1/β2 adrenoceptor antagonist of high potency used in the research of hypertension. Carazolol is also a potent, selective β3-adrenoceptor agonist[1].
Carazolol (0.01 mg/kg; i.m.; once) shows no significant side effects[2].

Reference

[1]. A Méjean, et al. Carazolol: a potent, selective beta 3-adrenoceptor agonist. Eur J Pharmacol. 1995 Nov 30;291(3):359-66.
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[2]. Remzi Gonul, et al. Effects of carazolol on electrocadiographic and trace element status in sheeps. Insights Vet Sci. 2018; 2: 001- 004.