For research use only. Not for therapeutic Use.
Carbazeran, a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran can be used for the research of metabolic disease[1].
| Catalog Number | R055269 |
| CAS Number | 70724-25-3 |
| Synonyms | [1-(6,7-dimethoxyphthalazin-1-yl)piperidin-4-yl] N-ethylcarbamate |
| Molecular Formula | C18H24N4O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H24N4O4/c1-4-19-18(23)26-13-5-7-22(8-6-13)17-14-10-16(25-3)15(24-2)9-12(14)11-20-21-17/h9-11,13H,4-8H2,1-3H3,(H,19,23) |
| InChIKey | QJGVXJYGDBSPSJ-UHFFFAOYSA-N |
| SMILES | CCNC(=O)OC1CCN(CC1)C2=NN=CC3=CC(=C(C=C32)OC)OC |
| Reference | [1]. Uehara S, et al. Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metab Dispos. 2020 Jul;48(7):580-586. |
