Carbendazim

• CAT Number: R013233
• CAS Number: 10605-21-7
• Molecular Formula: C₉H₉N₃O₂
• Molecular Weight: 191.19
• Purity: ≥95%
• Synonyms: N-1H-Benzimidazol-2-yl-carbamic Acid Methyl Ester; 2-Benzimidazolecarbamic Acid Methyl Ester; Carbendazole; BMC; MBC; BCM; BAS-3460; BAS-67054; CTR-6669; Albendazole Impurity E (EP); USP Fenbendazole Related Compound A
• Target: Fungal
• Storage: -20°C
• IUPAC Name: methyl N-(1H-benzimidazol-2-yl)carbamate
• InChI: InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)
• InChIKey: TWFZGCMQGLPBSX-UHFFFAOYSA-N
• SMILES: COC(=O)NC1=NC2=CC=CC=C2N1

Carbendazim（Cat No.:R013233）is a widely used systemic fungicide from the benzimidazole class. It works by inhibiting fungal microtubule formation and cell division. It controls a broad range of fungal diseases in crops such as cereals, fruits, vegetables, and ornamentals. Carbendazim is applied as a foliar spray or seed treatment, offering both protective and curative action. Although considered effective, concerns exist regarding its potential health and environmental impacts. Regulatory restrictions and reevaluations have occurred in some regions. Users must follow recommended guidelines to minimize residues and protect non-target organisms and surrounding ecosystems.

Reference

1:Hydrolysis mechanism of carbendazim hydrolase from the strain Microbacterium sp. djl-6F. Lei J, Wei S, Ren L, Hu S, Chen P.J Environ Sci (China). 2017 Apr;54:171-177. doi: 10.1016/j.jes.2016.05.027. Epub 2016 Jul 9. Review. PMID: 28391926 2:Rhamnolipid-aided biodegradation of carbendazim by Rhodococcus sp. D-1: Characteristics, products, and phytotoxicity. Bai N, Wang S, Abuduaini R, Zhang M, Zhu X, Zhao Y.Sci Total Environ. 2017 Jul 15;590-591:343-351. doi: 10.1016/j.scitotenv.2017.03.025. Epub 2017 Mar 6. PMID: 28279530 3:Catalyst-coated cement beads for the degradation and mineralization of fungicide carbendazim using laboratory and pilot-scale reactor: catalyst stability analysis. Singh A, Verma A, Bansal P, Aggarwal K, Kaur T, Toor AP, Sangal VK.Environ Technol. 2017 Mar 18:1-9. doi: 10.1080/09593330.2017.1302000. [Epub ahead of print] PMID: 28278085 4:Selection and Characterization of DNA Aptamers for Electrochemical Biosensing of Carbendazim. Eissa S, Zourob M.Anal Chem. 2017 Mar 7;89(5):3138-3145. doi: 10.1021/acs.analchem.6b04914. Epub 2017 Feb 10. PMID: 28264568 5:Transfer Assessment of Carbendazim Residues from Rape Flowers to Apicultural Products. Li YH, Zhou BL, Qian MR, Wang Q, Zhang H.J Anal Methods Chem. 2017;2017:6075405. doi: 10.1155/2017/6075405. Epub 2017 Jan 26. PMID: 28246574 Free PMC Article6:Identification of the key amino acid sites of the carbendazim hydrolase (MheI) from a novel carbendazim-degrading strain Mycobacterium sp. SD-4. Zhang Y, Wang H, Wang X, Hu B, Zhang C, Jin W, Zhu S, Hu G, Hong Q.J Hazard Mater. 2017 Jun 5;331:55-62. doi: 10.1016/j.jhazmat.2017.02.007. Epub 2017 Feb 16. PMID: 28242529 7:Complete Genome Sequence of Carbendazim-Degrading Mycobacterium sp. Strain djl-10. Zhang J, Yuan Q, Yang W, Wang X.Genome Announc. 2017 Feb 23;5(8). pii: e01683-16. doi: 10.1128/genomeA.01683-16. PMID: 28232422 Free PMC Article8:Electromembrane extraction and preconcentration of carbendazim and thiabendazole in water samples before capillary electrophoresis analysis. Oliveira AM, Loureiro HC, de Jesus FF, de Jesus DP.J Sep Sci. 2017 Apr;40(7):1532-1539. doi: 10.1002/jssc.201601305. Epub 2017 Mar 7. PMID: 28165201 9:Effects of superabsorbent polymers on the fate of fungicidal carbendazim in soils. Yang Y, Wang H, Huang L, Zhang S, He Y, Gao Q, Ye Q.J Hazard Mater. 2017 Apr 15;328:70-79. doi: 10.1016/j.jhazmat.2016.12.057. Epub 2017 Jan 8. PMID: 28103488 10:6-Gingerol-rich fraction prevents disruption of histomorphometry and marker enzymes of testicular function in carbendazim-treated rats. Salihu M, Ajayi BO, Adedara IA, Farombi EO.Andrologia. 2017 Jan 19. doi: 10.1111/and.12782. [Epub ahead of print] PMID: 28102023