For research use only. Not for therapeutic Use.
Carbenicillin Disodium（Cat No.:I005575）is a broad-spectrum, beta-lactam antibiotic in the penicillin class, effective against Gram-negative bacteria, including Pseudomonas aeruginosa and Proteus species. Often used to treat urinary tract, respiratory, and gastrointestinal infections, it inhibits bacterial cell wall synthesis, leading to cell lysis. Carbenicillin Disodium is widely used in molecular biology for selecting plasmid-containing bacteria due to its stability and effectiveness in culture media. Its disodium salt form improves solubility, making it suitable for intravenous administration, and is particularly valuable in research and clinical settings for combating resistant bacterial strains.
| Catalog Number | I005575 |
| CAS Number | 4800-94-6 |
| Synonyms | Carbenicillin Disodium; Carbenicillin sodium; Carbenicillin disodium salt; Carbecin; Sodium carbenicillin.;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxyphenylacetyl)amino)-3,3-dimethyl-7-oxo, disodium salt, (6S-(2alpha,5alpha,6beta |
| Molecular Formula | C17H16N2Na2O6S |
| Purity | ≥95% |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4°C for short term ,or -20 °C for long term |
| IUPAC Name | disodium;(2S,5R,6R)-6-[(2-carboxylato-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| InChI | InChI=1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1 |
| InChIKey | RTYJTGSCYUUYAL-YCAHSCEMSA-L |
| SMILES | CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)[O-])C(=O)[O-])C.[Na+].[Na+] |
| Reference | </br>1:Effect of tobramycin on the stability of carbenicillin disodium. Gupta VD, Stewart KR.Am J Hosp Pharm. 1983 Jun;40(6):1013-6. No abstract available. PMID: 6869386 </br>2:Effects of particulate matter from carbenicillin disodium solution on human macrophages in vitro. Tabaka MS, Bollinger RO, McClain PR, Ottenbreit M.Am J Hosp Pharm. 1981 Oct;38(10):1503-7. PMID: 7294046 </br>3:Quantitation of carbenicillin disodium, cefazolin sodium, cephalothin sodium, nafcillin sodium, and ticarcillin disodium by high-pressure liquid chromatography. Gupta VD, Stewart KR.J Pharm Sci. 1980 Nov;69(11):1264-7. PMID: 7452453 </br>4:Study of particulate matter in carbenicillin disodium using scanning electron microscopy and microbeam x-ray spectrography. Bollinger RO, Preuss AM, McClain PR, Hill WT Jr.Am J Hosp Pharm. 1978 Mar;35(3):312-7. PMID: 626212 |
