Carbonic anhydrase, Bovine erythrocytes

• CAT Number: I042449
• CAS Number: 9001-03-0
• Purity: ≥95%

Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy[1][2].
Applied to CO2 determination in blood,elimination of CO2 in reagents for acidity testing,carboxy group transfers,reduction reactions.
Solution preparation
Dissolve lyophilized powder at a concentration of 0.1 mg/mL in ice cold water. Store in ice bath prior to use. Immediately prior to use dilute suspensions or lyophilized materials to a concentration of approximately 0.01 mg/mL in ice cold water.

Reference

[1]. Kanchan Aggarwal, et al. In Situ Photoregulation of Carbonic Anhydrase Activity Using Azobenzenesulfonamides. Biochemistry. 2019 Jan 8;58(1):48-53.
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[2]. Vladimir Amirkhanov, et al. Pharmacophores Modeling in Terms of Prediction of Theoretical Physicochemical Properties and Verification by EXPERIMENTAL correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors. Mini Rev Med Chem. 2019;19(12):1015-1027.
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